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- 题名/责任者:
- Exon skipping : methods and protocols / edited by Annemieke Aartsma-Rus.
- 出版发行项:
- New York : Humana Press, c2012.
- ISBN:
- 9781617797668 (hbk.)
- ISBN:
- 1617797669 (hbk.)
- ISBN:
- 9781617797675 (e-ISBN)
- 载体形态项:
- xi, 440 p. : ill. (some col.) ; 27 cm.
- 丛编说明:
- Methods in molecular biology, 1064-3745 ; 867
- 丛编说明:
- Springer protocols
- 丛编统一题名:
- Methods in molecular biology (Clifton, N.J.) ; 867.
- 丛编统一题名:
- Springer protocols.
- 附加个人名称:
- Aartsma-rus, Annemieke M.
- 论题主题:
- Exons (Genetics)-Laboratory manuals.
- 论题主题:
- Exons-genetics-Laboratory Manuals.
- 论题主题:
- Genetic Techniques-Laboratory Manuals.
- 中图法分类号:
- Q523-33
- 书目附注:
- Includes bibliographical references and index.
- 内容附注:
- DNA diagnostics and exon skipping / Umasuthan Srirangalingam and Shern L. Chew -- Bioinformatics and mutations leading to exon skipping / F.O. Desmet and C. B茅roud -- Minigenes to confirm exon skipping mutations / Lourdes R. Desviat, Bel茅n P茅rez, and Magdalena Ugarte -- Analysis and interpretation of RNA splicing alterations in genes involved in genetic disorders / Maaike P.G. Vreeswijk and Heleen M. van der Klift -- Exon skipping mutations in neurofibromatosis / Emanuele Buratti and Diana Baralle -- Overview on applications of antisense-mediated exon skipping / Willeke M.C. van Roon-Mom and Annemieke Aartsma-Rus -- Overview on DMD exon skipping / Annemieke Aartsma-Rus -- Overview on AON design / Annemieke Aartsma-Rus -- Optimizing RNA/ENA chimeric antisense oligonucleotides using in vitro splicing / Yasuhiro Takeshima, Mariko Yagi, and Masafumi Matsuo --^
- 内容附注:
- Optimizing antisense oligonucleotides using phophorodiamidate morpholino oligomers / Linda J. Popplewell, Alberto Malerba, and George Dickson -- Optimizing splice-switching oligomer sequences using 2'-O-methyl phosphorothioate chemistry / Carl Adkin, Sue Fletcher, and Steve D. Wilton -- Exon skipping quantification by real-time PCR / Alessandra Ferlini and Paola Rimessi -- Antisense-mediated exon skipping to shift alternative splicing to treat cancer / Jing Wan -- Antisense-mediated exon skipping to generate soluble receptors / A. Seda Yilmaz-Elis and J. Sjef Verbeek -- Antisense-mediated exon skipping to reframe transcripts / Sandrina Turczynski ... [et al.] -- U1 snRNA as an effective vector for stable expression of antisense molecules and for the inhibition of the splicing reaction / Julie Martone, Fernanda Gabriella De Angelis, and Irene Bozzoni -- Engineering U7snRNA gene to reframe transcripts / Aur茅lie Goyenvalle --^
- 内容附注:
- Dynamic fluorescent and luminescent reporters for cell-based splicing screens / Claude C. Warzecha, Ruben Hovhannisyan, and Russ P. Carstens -- Antisense-mediated exon-skipping to induce gene knockdown / Petra Disterer and Bernard Khoo -- Antisense-mediated exon inclusion / Yimin Hua and Adrian R. Krainer -- Antisense genes to induce exon inclusion / Rachel Nlend Nlend and Daniel Sch眉mperli -- Using mini-genes to identify factors that modulate alternative splicing / Robert Morse, Adrian G. Todd, and Philip J. Young -- Overview of alternative oligonucleotide chemistries for exon skipping / Amer F. Saleh, Andrey A. Arzumanov, and Michael J. Gait -- Identification of peptides for tissue-specific delivery / Hans Heemskerk -- Systemic delivery of antisense oligomer in animal models and its implications for treating DMD / Qi Long Lu and Bo Wu -- Cell-penetrating peptides enhance systemic delivery of antisense morpholino oligomers / Hong M. Moulton --^
- 内容附注:
- Optimizing tissue-specific antisense oligonucleotide-peptide conjugates / Corinne A. Betts ... [et al.]
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