中南民族大学图书馆书目检索系统

Online Public Access Catalogue

题名/责任者:

Statistical issues in drug development / Stephen Senn.

版本说明:

2nd ed.

出版发行项:

Chichester, England ; Hoboken, NJ : John Wiley & Sons, c2007.

ISBN:

9780470018774 (cloth : alk. paper)

ISBN:

0470018771 (cloth : alk. paper)

载体形态项:

xix, 498 p. : ill. ; 25 cm.

丛编题名:

Statistics in practice

个人责任者:

Senn, Stephen.

论题主题:

Drug development-Statistical methods.

论题主题:

Clinical Trials as Topic.

论题主题:

Drug Design.

论题主题:

Statistics as Topic-methods.

中图法分类号:

R965

书目附注:

Includes bibliographical references and index.

内容附注:

A brief and superficial history of statistics for drug developers -- Design and interpretation of clinical trials as seen by a statistician -- Probability, Bayes, P-values, tests of hypotheses, and confidence intervals -- The work of the pharmaceutical statistician -- Allocating treatments to patients in clinical trials -- Baselines and covariate information --

内容附注:

The measurement of treatment effects -- Demographic subgroups : representation and analysis -- Multiplicity -- Intention to treat, missing data and related matters -- One-sided and two-sided tests and other issues to do with significance and P-values -- Determining the sample size -- Multicentre trials -- Active control equivalence studies --

内容附注:

Meta-analysis -- Cross-over trials -- n-of-1 trials -- Sequential trials -- Dose-finding -- Concerning pharmacokinetics and pharmacodynamics -- Bioequivalence studies -- Safety data, harms, drug monitoring, and pharmaco-epidemiology -- Pharmaco-economics and portfolio management -- Concerning pharmacogenetics, pharmacogenomics, and related matters.

豆瓣简介：