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题名/责任者:

Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations / edited by Sara E. Rosenbaum.

版本说明:

Second edition.

出版发行项:

Hoboken, New Jersey : John Wiley & Sons, Inc., [2017]

ISBN:

9781119143154 (pbk.)

载体形态项:

xxiii, 552 pages : illustrations ; 26 cm.

个人责任者:

Rosenbaum, Sara (Sara E.), author, editor.

论题主题:

Pharmacokinetics

论题主题:

Pharmacological Phenomena

论题主题:

Computer Simulation

中图法分类号:

R969.1

书目附注:

Includes bibliographical references and index.

内容附注:

Introduction to pharmacokinetics and pharmacodynamics -- Passage of drugs through membranes -- Drug administration and drug absorption / Steven Sutton -- Drug distribution -- Drug elimination and clearance -- Compartmental models in pharmacokinetics -- Pharmacokinetics of an intravenous bolus injection in a one-compartment model -- Pharmacokinetics of an intravenous bolus injection in a two-compartment model -- Pharmacokinetics of extravascular drug administration / Steven Sutton -- Introduction to noncompartmental analysis -- Pharmacokinetics of intravenous infusion in a one-compartment model -- Multiple intravenous bolus injections in the one-compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacogenetics -- Models used to predict drug-drug interactions for orally administered drugs -- Introduction to physiologically based pharmacokinetic modeling -- Introduction to pharmacodynamic models and integrated pharmacokinetic--pharmacodynamic models / Diane Mould and Paul Hutson -- Semi-mechanistic pharmacokinetic--pharmacodynamic model / Diane Mould and Paul Hutson.

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