MARC状态：审校 文献类型：西文图书 浏览次数：105
- 题名/责任者:
- G protein-coupled receptor screening assays : methods and protocols / edited by Sofia Aires M. Martins, Duarte Miguel F. Prazeres.
- 版本说明:
- Second edition.
- 出版发行项:
- New York, NY : Humana Press, [2021]
- ISBN:
- 9781071612200
- 载体形态项:
- xvi, 327 pages : illustrations (some color) ; 26 cm.
- 丛编说明:
- Methods in molecular biology, 1064-3745
- 附加个人名称:
- Martins, Sofia Aires M., editor.
- 附加个人名称:
- Prazeres, Duarte Miguel F., editor.
- 论题主题:
- G proteins-Receptors-Laboratory manuals.
- 论题主题:
- Drug development.
- 中图法分类号:
- Q26
- 一般附注:
- Includes index.
- 摘要附注:
- This fully updated edition targets not only those assays directly involved in the discovery of GPCR-active compounds but also those involved in cell-based experiments designed to study physiological responses. Whether coming from academia or industry, or being an experienced researcher or a newcomer to the field, the reader will find accessible methods and protocols that cover the latest developments on receptor purification, molecular biology, recombinant engineering, and analytical techniques that enable the real time monitoring of the complex GPCR signaling cascade and identification of potential drug targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, G Protein-Coupled Receptor Screening Assays: Methods and Protocols, Second Edition aims to provide the tools necessary to contribute to the advancement of GPCR research and discovery and ultimately lead to the availability of innovative and more efficient drugs.
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