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Online Public Access Catalogue

题名/责任者:

Signal detection for medical scientists : likelihood ratio test-based methodology / Ram Tiwari, Jyoti Zalkikar, Lan Huang.

版本说明:

First edition.

出版发行项:

Boca Raton : CRC Press, 2021.

ISBN:

9780367201432

ISBN:

0367201437

载体形态项:

xvii, 226 pages : illustrations (black and white) ; 24 cm.

其他载体形态:

Online version: Tiwari, Ram (Ram C.) Signal detection for medical scientists. First edition Boca Raton : CRC Press, 2021. 9780429259753

丛编说明:

Chapman & Hall/CRC Biostatistics series

个人责任者:

Tiwari, Ram (Ram C.), author.

附加个人名称:

Zalkikar, Jyoti, author.

附加个人名称:

Huang, Lan (Statistician), author.

论题主题:

Drugs-Testing-Statistical methods.

论题主题:

Signal detection-Statistical methods.

论题主题:

Statistical hypothesis testing.

论题主题:

Data mining-Statistical methods.

中图法分类号:

R911

书目附注:

Includes bibliographical references (pages 211-223) and index.

内容附注:

Data mining methods for signal detection -- Basic LRT method -- LRT methods for drug classes -- ZIP-LRT method for modeling extra-zeros -- LRT method for active safety surveillance with exposure information -- LRT-based methodologies for analysis of multiple studies -- LRT methods in medical device safety evaluation -- LRT method for multiple-site device data with continuous outcomes -- Use of LRT in site selection.

摘要附注:

"This book presents the data mining techniques with focus on likelihood ratio test (LRT) based methods for signal detection. It emphasizes computational aspect of LRT methodology and is pertinent for first-time researchers and graduate students venturing into this interesting field. The book is written as a reference book for professionals in pharmaceutical industry, manufactures of medical devices, and regulatory agencies. The book deals with the signal detection in drug/device evaluation, which is important in the post-market evaluation of medical products, and in the pre-market signal detection during clinical trials for monitoring procedures"--

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