机读格式显示(MARC)

• 000 02477pam 22003134a 4500

• 001 0000393195

• 003 SCNU

• 005 20051212113634.0

• 008 031124s2005 nyua b 001 0 eng

• 010 __ |a 2003025851

• 020 __ |a 0816049483 (alk. paper)

• 040 __ |a DLC |c DLC |d OCO |d XY4 |d C#P

• 092 0_ |a 615.895 |b P194g

• 093 __ |a R730.2 |2 4

• 100 1_ |a Panno, Joseph.

• 245 10 |a Gene therapy : |b treating disease by repairing genes / |c Joseph Panno.

• 260 __ |a New York, NY : |b Facts On File, |c c2005.

• 300 __ |a xvii, 172 p. : |b ill. ; |c 23 cm.

• 440 _0 |a Facts on File science library.

• 490 1_ |a The "new biology" series.

• 504 __ |a Includes bibliographical references (p. 151-155) and index.

• 505 0_ |a Genetic disorders -- Immune deficiencies -- Breast cancer -- Colon cancer -- Melanoma -- Cystic fibrosis -- Hemophilia -- Liver disease -- Cardiovascular disease -- Muscular dystrophy -- Alzheimer's disease -- Parkinson's disease -- Huntington's disease -- Viruses: the cornerstone of gene therapy -- Viruses are living crystals -- Viral genomes may be RNA or DNA -- Viruses evolved from plasmids -- Viruses know how to infect cells -- The virus as a gene vehicle -- Viruses used in gene therapy -- Ashi DeSilva: a promising start -- Clinical trials defined -- Cells of the immune system -- Adenosine deaminase (ADA) -- Preliminary research -- Clinical procedure for ADA gene therapy -- The DeSilva clinical trial -- Jesse Gelsinger: down to earth -- Ornithine transcarbamylase (OTC) -- Preliminary research -- Clinical procedure for OTC gene therapy -- The Gelsinger clinical trial -- The investigation -- Concluding remarks -- Future prospects -- Safer vehicles -- Reducing immune rejection of the vector -- Improved risk assessment -- Redesigning human anatomy and physiology -- Ethics of gene therapy -- The Belmont report -- Clinical trials -- Physiological enhancement -- Cosmetic applications -- Legal issues -- Regulatory agencies -- The Gelsinger legal trial -- International regulation -- Resource center -- Eucaryote cell primer -- Recombinant DNA primer -- The human genome project -- X-linked severe combined immunodeficiency (SCID-X1) -- Alzheimer's disease (AD) -- Huntington's disease (HD).

• 650 _0 |a Gene therapy.

• 800 1_ |a Panno, Joseph. |t New biology.

• 950 __ |a SCNU |f R730.2/P194

• 999 __ |M zxq |m 20051212 11:36:34 |G zxq |g 20051212 11:37:05

• 000 1000006483

• 991 __ |a 022005002011

• 907 __ |a SCNU |f R730.2/P194