机读格式显示(MARC)

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• 003 SCNU

• 005 20230105115700.0

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• 010 __ |a 2020056852

• 016 7_ |a 020171491 |2 Uk

• 020 __ |a 9780367201432

• 020 __ |a 0367201437

• 020 __ |z 9780429259753

• 020 __ |z 9780429535390

• 020 __ |z 9780429521928

• 040 __ |a LBSOR/DLC |b eng |e rda |c DLC |d OCLCO |d OCLCF |d UKMGB

• 050 00 |a RM301.27 |b .T59 2021

• 082 00 |a 615.1072/4 |2 23

• 093 __ |a R911 |2 5

• 099 __ |a CAL 022022013332

• 100 1_ |a Tiwari, Ram |q (Ram C.), |e author.

• 245 10 |a Signal detection for medical scientists : |b likelihood ratio test-based methodology / |c Ram Tiwari, Jyoti Zalkikar, Lan Huang.

• 250 __ |a First edition.

• 264 _1 |a Boca Raton : |b CRC Press, |c 2021.

• 300 __ |a xvii, 226 pages : |b illustrations (black and white) ; |c 24 cm.

• 336 __ |a text |b txt |2 rdacontent

• 337 __ |a unmediated |b n |2 rdamedia

• 338 __ |a volume |b nc |2 rdacarrier

• 490 0_ |a Chapman & Hall/CRC Biostatistics series

• 504 __ |a Includes bibliographical references (pages 211-223) and index.

• 505 0_ |a Data mining methods for signal detection -- Basic LRT method -- LRT methods for drug classes -- ZIP-LRT method for modeling extra-zeros -- LRT method for active safety surveillance with exposure information -- LRT-based methodologies for analysis of multiple studies -- LRT methods in medical device safety evaluation -- LRT method for multiple-site device data with continuous outcomes -- Use of LRT in site selection.

• 520 __ |a "This book presents the data mining techniques with focus on likelihood ratio test (LRT) based methods for signal detection. It emphasizes computational aspect of LRT methodology and is pertinent for first-time researchers and graduate students venturing into this interesting field. The book is written as a reference book for professionals in pharmaceutical industry, manufactures of medical devices, and regulatory agencies. The book deals with the signal detection in drug/device evaluation, which is important in the post-market evaluation of medical products, and in the pre-market signal detection during clinical trials for monitoring procedures"-- |c Provided by publisher.

• 650 _0 |a Drugs |x Testing |x Statistical methods.

• 650 _0 |a Signal detection |x Statistical methods.

• 650 _0 |a Statistical hypothesis testing.

• 650 _0 |a Data mining |x Statistical methods.

• 700 1_ |a Zalkikar, Jyoti, |e author.

• 700 1_ |a Huang, Lan |c (Statistician), |e author.

• 776 08 |i Online version: |a Tiwari, Ram (Ram C.) |t Signal detection for medical scientists. |b First edition |d Boca Raton : CRC Press, 2021. |z 9780429259753 |w (DLC) 2020056853

• 920 __ |a 242430 |z 1

• 950 __ |a SCNU |f R911/T623