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- 000 02351cam a2200325 i 4500
- 008 210616s2021 nyua 001 0 eng d
- 020 __ |a 9781071612200 |q print : |c CNY1200.13
- 040 __ |a GW5XE |b eng |c GW5XE |e rda |d AU@ |d OCLCO
- 245 00 |a G protein-coupled receptor screening assays : |b methods and protocols / |c edited by Sofia Aires M. Martins, Duarte Miguel F. Prazeres.
- 250 __ |a Second edition.
- 264 _1 |a New York, NY : |b Humana Press, |c [2021]
- 300 __ |a xvi, 327 pages : |b illustrations (some color) ; |c 26 cm.
- 336 __ |a text |b txt |2 rdacontent
- 337 __ |a unmediated |b n |2 rdamedia
- 338 __ |a volume |b nc |2 rdacarrier
- 490 1_ |a Methods in molecular biology, |x 1064-3745
- 500 __ |a Includes index.
- 520 __ |a This fully updated edition targets not only those assays directly involved in the discovery of GPCR-active compounds but also those involved in cell-based experiments designed to study physiological responses. Whether coming from academia or industry, or being an experienced researcher or a newcomer to the field, the reader will find accessible methods and protocols that cover the latest developments on receptor purification, molecular biology, recombinant engineering, and analytical techniques that enable the real time monitoring of the complex GPCR signaling cascade and identification of potential drug targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, G Protein-Coupled Receptor Screening Assays: Methods and Protocols, Second Edition aims to provide the tools necessary to contribute to the advancement of GPCR research and discovery and ultimately lead to the availability of innovative and more efficient drugs.
- 650 _0 |a G proteins |x Receptors |v Laboratory manuals.
- 650 _0 |a Drug development.
- 700 1_ |a Martins, Sofia Aires M., |e editor.
- 700 1_ |a Prazeres, Duarte Miguel F., |e editor.
- 830 _0 |a Methods in molecular biology (Clifton, N.J.)
- 950 __ |a SCNU |f Q26/M386-2