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Online Public Access Catalogue

题名/责任者:

Gene therapy : treating disease by repairing genes / Joseph Panno.

出版发行项:

New York, NY : Facts On File, c2005.

ISBN:

0816049483 (alk. paper)

载体形态项:

xvii, 172 p. : ill. ; 23 cm.

丛编题名:

Facts on File science library.

丛编说明:

The "new biology" series.

个人责任者:

Panno, Joseph.

丛编个人名称:

Panno, Joseph. New biology.

论题主题:

Gene therapy.

中图法分类号:

R730.2

书目附注:

Includes bibliographical references (p. 151-155) and index.

内容附注:

Genetic disorders -- Immune deficiencies -- Breast cancer -- Colon cancer -- Melanoma -- Cystic fibrosis -- Hemophilia -- Liver disease -- Cardiovascular disease -- Muscular dystrophy -- Alzheimer's disease -- Parkinson's disease -- Huntington's disease -- Viruses: the cornerstone of gene therapy -- Viruses are living crystals -- Viral genomes may be RNA or DNA -- Viruses evolved from plasmids -- Viruses know how to infect cells -- The virus as a gene vehicle -- Viruses used in gene therapy -- Ashi DeSilva: a promising start -- Clinical trials defined -- Cells of the immune system -- Adenosine deaminase (ADA) -- Preliminary research -- Clinical procedure for ADA gene therapy -- The DeSilva clinical trial -- Jesse Gelsinger: down to earth -- Ornithine transcarbamylase (OTC) -- Preliminary research -- Clinical procedure for OTC gene therapy -- The Gelsinger clinical trial -- The investigation -- Concluding remarks -- Future prospects -- Safer vehicles -- Reducing immune rejection of the vector -- Improved risk assessment -- Redesigning human anatomy and physiology -- Ethics of gene therapy -- The Belmont report -- Clinical trials -- Physiological enhancement -- Cosmetic applications -- Legal issues -- Regulatory agencies -- The Gelsinger legal trial -- International regulation -- Resource center -- Eucaryote cell primer -- Recombinant DNA primer -- The human genome project -- X-linked severe combined immunodeficiency (SCID-X1) -- Alzheimer's disease (AD) -- Huntington's disease (HD).

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